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Brandon Aiyuk
Brandon Aiyuk Still no timetable to practice
Mon, Oct 13, 2025, 5:30 PM
Coach Kyle Shanahan said Monday that Aiyuk (knee) is getting "closer and closer" to being able to practice, but the 49ers don't have a specific timeline for the wide receiver to do so, Nick Wagoner of ESPN.com reports.
Analysis: Aiyuk remains in recovery mode from the ACL and MCL tears that he suffered in his right knee Week 7 of last season, instead residing on the reserve/PUP list to this point in the campaign. Per David Lombardi of SFStandard.com, Shanahan added, "I always look around Week 10, but I'm not putting an exact date on it." As of Week 6, Aiyuk's only notable on-field work occurred in mid-September, when he was seen running while fellow 49ers wide receivers worked in individual drills, per Wagoner.
Ricky Pearsall
Ricky Pearsall Could practice Wednesday
Mon, Oct 13, 2025, 5:23 PM
Coach Kyle Shanahan said Monday that Pearsall (knee) will be evaluated Wednesday to see if he'll be able to practice this week, Nick Wagoner of ESPN.com reports.
Analysis: Pearsall has missed two weeks of practice since injuring the PCL in his right knee Week 4 against the Jaguars, but like QB Brock Purdy, the wide receiver resumed conditioning work on the side last Thursday, indicating that he's making progress in his recovery. Wednesday's practice report will reveal whether or not Pearsall was able to mix into drills, but the 49ers appear to be getting healthier, with Purdy and TE George Kittle (hamstring) all potentially returning to practice in the near future.
Brock Purdy
Brock Purdy May practice Wednesday
Mon, Oct 13, 2025, 5:18 PM
Coach Kyle Shanahan said Monday that Purdy (toe) will be evaluated Wednesday to see if the quarterback will be able to practice this week, Nick Wagoner of ESPN.com reports.
Analysis: Since aggravating a turf toe injury Week 4, Purdy hasn't mixed into any drills, but he resumed conditioning work on the side last Thursday, signaling that he's making progress in his recovery. He's missed four games in all due to the health concern (Weeks 2-3 and 5-6), with backup Mac Jones filling in well during Purdy's absence. If Purdy is able to practice Wednesday, he could be on a path to return to action this coming Sunday versus the Falcons.
George Kittle
George Kittle In line to practice this week
Mon, Oct 13, 2025, 5:13 PM
Coach Kyle Shanahan said Monday that the 49ers expect Kittle (hamstring) to practice this week, Nick Wagoner of ESPN.com reports.
Analysis: San Francisco has yet to designate Kittle to return from injured reserve, which will need to happen for the tight end to mix into drills. The team resumes practicing Wednesday in advance of next Sunday's game against the Falcons, meaning the aforementioned transaction may transpire before then. In any case, Kittle appears poised to put the finishing touches on his recovery from the hamstring injury that has sidelined him since Week 1.
Marquez Valdes-Scantling
Marquez Valdes-Scantling Grabs two receptions Sunday
Mon, Oct 13, 2025, 12:48 PM
Valdes-Scantling had two receptions on three targets for 22 yards in Sunday's 30-19 loss to the Buccaneers.
Analysis: Valdes-Scantling wound up playing 42 snaps (61 percent) on offense while serving as the No. 3 receiver against Tampa Bay. The 30-year-old more than doubled his entire season production with Sunday's output, which highlights his lack of usage through six weeks. Valdes-Scantling will look to stay involved against the Falcons next Sunday, but there is little to see from a fantasy perspective.
Skyy Moore
Skyy Moore No touches on offense
Mon, Oct 13, 2025, 12:18 PM
Moore logged three snaps (four percent) on offense and did not record a touch while generating 134 return yards on six combined attempts in Sunday's 30-19 loss to Tampa Bay.
Analysis: Moore reverted to primarily operating as the 49ers' punt and kick returner after recording at least one target or one carry over his previous three appearances. The 24-year-old has just one reception for 10 yards in six appearances this season, leaving no room for fantasy utility. The song remains the same for Moore in next Sunday's tilt against Atlanta.
Brian Robinson
Brian Robinson No rushing attempts Sunday
Mon, Oct 13, 2025, 11:50 AM
Robinson did not record a carry and caught all three of his targets for eight yards in Sunday's 30-19 loss to the Buccaneers.
Analysis: It was an odd usage game for Robinson after he did not receive a carry for the first time in six appearances this year. Equally abnormal, the veteran backup's three targets Sunday matched the combined total from his previous five contests. The end result was still unsavory from a fantasy perspective, as Robinson was unable to do much with just five snaps played on offense (seven percent). Fantasy managers shouldn't expect much from Robinson in games that starter Christian McCaffrey is healthy for. The same can be said for next Sunday's tilt against the Falcons.
Demarcus Robinson
Demarcus Robinson Gains 44 yards Sunday
Mon, Oct 13, 2025, 11:02 AM
Robinson had two receptions on three targets for 44 yards in Sunday's 30-19 loss to the Buccaneers.
Analysis: Robinson was demoted to No. 4 on the 49ers' depth chart with the return of Jauan Jennings (ribs) to the starting lineup Sunday. The 30-year-old Robinson still finished with his highest yardage total since joining San Francisco this past offseason after breaking off a 31-yard reception in the second quarter. Robinson only logged 13 snaps (19 percent) for a shorthanded offense Sunday, a concerning trend for a player who was expected to step into a larger role with his new club. The veteran wideout makes for a risky play in Week 7 against the Falcons with such a limited role.
Jake Tonges
Jake Tonges Strong PPR effort Sunday
Sun, Oct 12, 2025, 9:12 PM
Tonges corralled six of seven targets for 57 yards in Sunday's 30-19 loss to Tampa Bay.
Analysis: Tonges continued doing his best George Kittle (hamstring) impression in another effective spot-start Sunday. The 25-year-old Tonges has been a pleasant surprise in fantasy during his brief run as the starter, posting a 25-223-3 receiving line through six games. David Lombardi of SFStandard.com reported that Kittle could return from injured reserve in Week 7, which would effectively end Tonges' run of utility. Managers should wait until Kittle is officially activated before making any rash decisions regarding Tonges in Week 7 and onward.
Kendrick Bourne
Kendrick Bourne Matches last week's career output
Sun, Oct 12, 2025, 8:39 PM
Bourne finished with five receptions on nine targets for 142 yards in Sunday's 30-19 loss to the Buccaneers.
Analysis: Fresh off posting a career-best 142 receiving yards against the Rams in Week 5, Bourne likely made his managers double take at the box score after hitting that same mark in consecutive contests. The 29-year-old has shown great chemistry with old teammate Mac Jones, as the former Patriots continue to post video game numbers filling in for injured 49ers' starters in 2025. Bourne continued starting in place of Ricky Pearsall (knee) while Jauan Jennings (ribs) returned in a limited capacity but revealed that he was playing with five broken ribs after the contest. If Pearsall is forced to miss a third-consecutive game in Week 7, then Bourne's stock would remain elevated for next Sunday's tilt against the Falcons. Either way, managers should continue riding the receiver's hot streak until the wheels fall off.
Mac Jones
Mac Jones Throws two picks in losing effort
Sun, Oct 12, 2025, 7:55 PM
Jones (knee/oblique) completed 27 of 39 pass attempts for 347 yards and two interceptions while rushing five times for 13 yards in Sunday's 30-19 loss to the Buccaneers.
Analysis: Jones toughed out a pair of injuries and another week of limited practices in order to start for a shorthanded 49ers squad Sunday. The veteran backup was unable to earn his fourth win in as many appearances with San Francisco, but he did produce a season-high 347 passing yards for fantasy managers. The Alabama product is averaging a whopping 313.0 yards per game with a 2:1 TD:INT in place of starter Brock Purdy (toe/shoulder) this season. The latter's status is currently unclear for Week 7, but Jones has certainly played well enough in Purdy's stead to warrant fantasy consideration if he remains under center against the Falcons for Sunday Night Football.
Christian McCaffrey
Christian McCaffrey Scores first rushing TD this season
Sun, Oct 12, 2025, 6:49 PM
McCaffrey took 17 carries for 54 yards and a touchdown while hauling in seven of eight targets for 57 yards in Sunday's 30-19 loss to the Buccaneers.
Analysis: McCaffrey scored his first regular-season touchdown since the 2023 campaign after being held out of the end zone as a runner over his previous five starts this year and all four healthy appearances in 2024. The dual-threat superstar has been in the doldrums as a pure rusher this season (3.1 YPC), but he has offset that with WR1 production as a receiver (46-444-3). In fact, CMC has finished with more receiving yards than rushing yards in five of his six starts this year, highlighting a peculiar start to his game logs. Fantasy managers could care less how their workhorse gets his numbers so long as the overall production is elite, as it has been all season. McCaffrey will likely be asked to continue shouldering the load for the 49ers' offense against the Falcons on Sunday Night Football in Week 7.
Jauan Jennings
Jauan Jennings Playing through broken ribs
Sun, Oct 12, 2025, 6:48 PM
Jennings said after Sunday's loss to the Bucs that he played with five broken ribs against Tampa Bay, David Lombardi of SFStandard.com reports.
Analysis: Jennings missed Week 5 against the Rams with the injury but returned to the lineup Sunday against Tampa Bay. However, he was almost nonexistent in the box score, finishing with just one catch for seven yards as an afterthought in the passing game. Jennings didn't look anywhere near 100 percent health. Kendrick Bourne turned in another stellar performance, securing five of nine targets for 142 yards as Mac Jones' preferred go-to option. Jennings will be hard to trust in fantasy lineups next Sunday against Atlanta.
Jordan James
Jordan James Won't play against Tampa Bay
Sun, Oct 12, 2025, 2:16 PM
James (coach's decision) is inactive for Sunday's game against the Buccaneers, Briana Jeannel of the 49ers' official site reports.
Analysis: The rookie fifth-rounder has yet to see regular-season action and will be a healthy scratch for a fifth consecutive game. Christian McCaffrey, Brian Robinson and Isaac Guerendo will serve as the 49ers' active running backs for Sunday's road tilt.
Jauan Jennings
Jauan Jennings Back in action Sunday
Sun, Oct 12, 2025, 2:05 PM
Jennings (ankle/rib) is listed as active Sunday at Tampa Bay, Briana Jeannel of the 49ers' official site reports.
Analysis: Jennings sat out a Week 5 win at the Rams due to the rib injury that he picked up during a Week 4 loss to the Jaguars. He managed to log limited sessions Thursday and Friday before the 49ers tagged him as questionable for Week 6 action. With his status now confirmed for Sunday's game, Jennings will return to a San Francisco offense that's without notables like QB Brock Purdy (toe, inactive), TE George Kittle (hamstring, IR) and Ricky Pearsall (knee, inactive). As a result, Jennings should slot in as one of QB Mac Jones' (knee) top targets along with RB Christian McCaffrey, WRs Kendrick Bourne and Demarcus Robinson and TE Jake Tonges.
Mac Jones
Mac Jones Active, starting again Sunday
Sun, Oct 12, 2025, 2:03 PM
Jones (knee/oblique) is active for Sunday's game in Tampa Bay, Briana Jeannel of the 49ers' official site reports.
Analysis: During a week in which Jones practiced in a limited capacity Wednesday through Friday due to the oblique injury that he suffered Week 5 and a lingering PCL sprain, he didn't attempt many passes until Friday, at which point the 49ers deemed him questionable for Week 6 action. With No. 1 QB Brock Purdy (toe) out yet again, Jones will earn his fourth start of the season after completing 86 of 129 passes (66.7 percent) for 905 yards, six touchdowns and one interception in his first three opportunities to lead the 49ers offense. Adam Schefter of ESPN reported overnight Saturday that Purdy has "a chance" to return next Sunday night against the Falcons, so Jones' time as San Francisco's starting QB may come to a close after this Sunday's contest.
Jauan Jennings
Jauan Jennings Slated to suit up Sunday
Sat, Oct 11, 2025, 11:23 PM
Jennings, who is questionable to play against Tampa Bay on Sunday due to an ankle injury, is expected to suit up, Adam Schefter of ESPN reports.
Analysis: Jennings missed last Thursday's Week 5 overtime win over the Rams due to an ankle issue and began this week of practice as a DNP before upgrading to limited sessions Thursday and Friday. That level of participation appears to be enough to allow him to make his return to the field against the Buccaneers in Week 6. If Jennings does indeed suit up, he should work as the team's top pass-catching option with Ricky Pearsall (knee) already ruled out and George Kittle (hamstring) still on IR. Jennings would be working with QB Mac Jones (oblique/knee), who is expected to start at QB with Brock Purdy (toe) set to miss another contest. Schefter notes that Pearsall and Purdy could return in Week 7, so San Francisco's injury-ravaged air attack seems to be slowly getting healthier.
Jauan Jennings
Jauan Jennings Potential game-time decision
Fri, Oct 10, 2025, 7:33 PM
Jennings (ankle) is listed as questionable and may be a game-time decision Sunday at Tampa Bay, ESPN.com's Nick Wagoner reports.
Analysis: QB Mac Jones (oblique/knee) is listed as questionable but fully expected to start, whereas Jennings is truly questionable and may end up coming down to the wire ahead of a 4: 25 p.m. ET kickoff Sunday. He was a limited practice participant Thursday and Friday, after missing Week 5 with ankle and rib injuries.
Mac Jones
Mac Jones Expected to start
Fri, Oct 10, 2025, 7:30 PM
Jones (knee) is expected to start Sunday's game at Tampa Bay, ESPN.com's Nick Wagoner reports.
Analysis: Jones is officially listed as questionable after being a limited practice participant all week. He was already playing through a PCL injury and is now set to play through an oblique injury as well, while fellow 49ers quarterback Brock Purdy (toe) has been ruled out for at least one more game.
Jordan Watkins
Jordan Watkins Remains sideined
Fri, Oct 10, 2025, 7:25 PM
Watkins (calf) has been ruled out for Sunday's game against the Buccaneers, Greg Auman of Fox Sports reports.
Analysis: Watkins will miss his fourth straight game and has yet to practice in any capacity since suffering the calf injury. He has yet to play this season after being a healthy scratch early in the campaign.

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